Enhanced Circadian Entrainment in Mice and Its Utility under Human Shiftwork Schedules
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چکیده
منابع مشابه
Both neuropeptide Y and serotonin are necessary for entrainment of circadian rhythms in mice by daily treadmill running schedules.
This study investigated the role of the suprachiasmatic nucleus (SCN) circadian pacemaker and its neuropeptide Y (NPY) and serotonin (5-HT) afferents in entrainment (synchronization) of mouse circadian rhythms by treadmill running. Blind C57BL/6j mice were run in treadmills for 3 hr/d for 3-10 weeks after receiving radio-frequency lesions of the SCN or the intergeniculate leaflet (IGL, the sour...
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ژورنال
عنوان ژورنال: Clocks & Sleep
سال: 2019
ISSN: 2624-5175
DOI: 10.3390/clockssleep1030032